Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infection.

Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infection.

Fatal outcomes of Ebola virus (EBOV) infections are typically preceded by a 'sepsis-like' syndrome and lymphopenia despite T cells being resistant to Ebola infection. The mechanisms that lead to T lymphocytes death remain largely unknown; however, the degree of lymphopenia is highly correl...

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Bibliographic Details
Main Authors: Mathieu Iampietro, Patrick Younan, Andrew Nishida, Mukta Dutta, Ndongala Michel Lubaki, Rodrigo I Santos, Richard A Koup, Michael G Katze, Alexander Bukreyev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5456411?pdf=render

Internet

http://europepmc.org/articles/PMC5456411?pdf=render

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