Safety, tolerability, and pharmacokinetics of repeated oral doses of 2-hydroxybenzylamine acetate in healthy volunteers: a double-blind, randomized, placebo-controlled clinical trial

Safety, tolerability, and pharmacokinetics of repeated oral doses of 2-hydroxybenzylamine acetate in healthy volunteers: a double-blind, randomized, placebo-controlled clinical trial

Abstract Background 2-Hydroxybenzylamine (2-HOBA) is a selective dicarbonyl electrophile scavenger being developed as a nutritional supplement to help protect against the development of conditions associated with dicarbonyl electrophile formation, such as the cognitive decline observed with Mild Cog...

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Bibliographic Details
Main Authors: Lisa M. Pitchford, Patricia M. Driver, John C. Fuller, Wendell S. Akers, Naji N. Abumrad, Venkataraman Amarnath, Ginger L. Milne, Sheau-Chiann Chen, Fei Ye, L. Jackson Roberts, M. Benjamin Shoemaker, John A. Oates, John A. Rathmacher, Olivier Boutaud
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Pharmacology and Toxicology
Subjects:
Safety
Pharmacokinetics
Humans
Salicylamine
γ-Ketoaldehydes
Online Access:https://doi.org/10.1186/s40360-020-0382-y

Internet

https://doi.org/10.1186/s40360-020-0382-y

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