In Vitro and In Vivo Anti-tumoral Effects of the Flavonoid Apigenin in Malignant Mesothelioma

In Vitro and In Vivo Anti-tumoral Effects of the Flavonoid Apigenin in Malignant Mesothelioma

Malignant mesothelioma (MM) is a tumor arising from mesothelium. MM patients’ survival is poor. The polyphenol 4′,5,7,-trihydroxyflavone Apigenin (API) is a “multifunctional drug”. Several studies have demonstrated API anti-tumoral effects. However, little is known on the in vitro and in vivo anti-t...

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Bibliographic Details
Main Authors: Laura Masuelli, Monica Benvenuto, Rosanna Mattera, Enrica Di Stefano, Erika Zago, Gloria Taffera, Ilaria Tresoldi, Maria Gabriella Giganti, Giovanni Vanni Frajese, Ginevra Berardi, Andrea Modesti, Roberto Bei
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Pharmacology
Subjects:
cancer
mesothelioma
apigenin
apoptosis
polyphenol
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00373/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00373/full

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