The Role of CXC Chemokine Receptors 1–4 on Immune Cells in the Tumor Microenvironment

Chemokines govern leukocyte migration by attracting cells that express their cognate ligands. Many cancer types show altered chemokine secretion profiles, favoring the recruitment of pro-tumorigenic immune cells and preventing the accumulation of anti-tumorigenic effector cells. This can ultimately...

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Bibliographic Details
Main Authors: Katharina Helene Susek, Maria Karvouni, Evren Alici, Andreas Lundqvist
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02159/full