Optimization of Catheter Based rtPA Thrombolysis in a Novel In Vitro Clot Model for Intracerebral Hemorrhage

Hematoma lysis with recombinant tissue plasminogen activator (rtPA) has emerged as an alternative therapy for spontaneous intracerebral hemorrhage (ICH). Optimal dose and schedule are still unclear. The aim of this study was to create a reliable in vitro blood clot model for investigation of optimal...

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Bibliographic Details
Main Authors: Naureen Keric, Julia Masomi-Bornwasser, Hendrik Müller-Werkmeister, Sven Rainer Kantelhardt, Jochem König, Oliver Kempski, Alf Giese
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2017/5472936