Age-Related Differential Structural and Transcriptomic Responses in the Hypertensive Heart

While aging is a critical risk factor for heart failure, it remains uncertain whether the aging heart responds differentially to a hypertensive stimuli. Here we investigated phenotypic and transcriptomic differences between the young and aging heart using a mineralocorticoid-excess model of hyperten...

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Bibliographic Details
Main Authors: Francine Z. Marques, Po-Yin Chu, Mark Ziemann, Antony Kaspi, Helen Kiriazis, Xiao-Jun Du, Assam El-Osta, David M. Kaye
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00817/full