QSAR analysis of some azole derivatives as potent aromatase inhibitors

A high proportion of breast tumors are hormone-dependent, implying that endogenous estrogens play a critical role in cancer cell proliferation. One of the most effective strategies for the treatment of breast cancer is reduction of estrogens level by inhibiting aromatase enzyme which is responsible...

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Bibliographic Details
Main Authors: Razeih Sabet, Soghra Khabnadideh, Samaneh Mohseni, Ayyub Mojaddami, Zahra Rezaei
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2018-12-01
Series:Trends in Pharmaceutical Sciences
Subjects:
Online Access:http://tips.sums.ac.ir/article_42266_386f2aa39f171cda0865e50ca004c573.pdf