Mapping, Structure and Modulation of PPI

Because of the key relevance of protein–protein interactions (PPI) in diseases, the modulation of protein-protein complexes is of relevant clinical significance. The successful design of binding compounds modulating PPI requires a detailed knowledge of the involved protein-protein system at molecula...

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Bibliographic Details
Main Authors: Elisa Martino, Sara Chiarugi, Francesco Margheriti, Gianpiero Garau
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.718405/full