A Drosophila model of high sugar diet-induced cardiomyopathy.

Diets high in carbohydrates have long been linked to progressive heart dysfunction, yet the mechanisms by which chronic high sugar leads to heart failure remain poorly understood. Here we combine diet, genetics, and physiology to establish an adult Drosophila melanogaster model of chronic high sugar...

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Bibliographic Details
Main Authors: Jianbo Na, Laura Palanker Musselman, Jay Pendse, Thomas J Baranski, Rolf Bodmer, Karen Ocorr, Ross Cagan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3542070?pdf=render