Androgen receptor decreases renal cell carcinoma bone metastases via suppressing the osteolytic formation through altering a novel circEXOC7 regulatory axis

Androgen receptor decreases renal cell carcinoma bone metastases via suppressing the osteolytic formation through altering a novel circEXOC7 regulatory axis

Abstract Background Clear cell renal cell carcinoma (ccRCC) has gender differences, with the androgen receptor (AR) linked positively with metastasis to the lung. Its linkage to ccRCC bone metastases (RBMs), however, remains unclear. Methods In the current study, five human RCC and five RCC bone met...

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Bibliographic Details
Main Authors: Dongkui Gong, Yin Sun, Changcheng Guo, Tzong‐jen Sheu, Wei Zhai, Junhua Zheng, Chawnshang Chang
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Clinical and Translational Medicine
Subjects:
androgen receptor
bone metastases
ccRCC
circEXOC7
CSF1
DHX9
Online Access:https://doi.org/10.1002/ctm2.353

Internet

https://doi.org/10.1002/ctm2.353

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