Soluble P‐tau217 reflects amyloid and tau pathology and mediates the association of amyloid with tau

Soluble P‐tau217 reflects amyloid and tau pathology and mediates the association of amyloid with tau

Abstract Alzheimer’s disease is characterized by β‐amyloid plaques and tau tangles. Plasma levels of phospho‐tau217 (P‐tau217) accurately differentiate Alzheimer’s disease dementia from other dementias, but it is unclear to what degree this reflects β‐amyloid plaque accumulation, tau tangle accumula...

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Bibliographic Details
Main Authors: Niklas Mattsson‐Carlgren, Shorena Janelidze, Randall J Bateman, Ruben Smith, Erik Stomrud, Geidy E Serrano, Eric M Reiman, Sebastian Palmqvist, Jeffrey L Dage, Thomas G Beach, Oskar Hansson
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:EMBO Molecular Medicine
Subjects:
Alzheimer’s disease
amyloid
phosphorylated tau
plasma
tau
Online Access:https://doi.org/10.15252/emmm.202114022

Internet

https://doi.org/10.15252/emmm.202114022

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