Brain Abscess as Severe Presentation of Specific Granule Deficiency

Brain Abscess as Severe Presentation of Specific Granule Deficiency

Severe invasive infections such as brain abscess in a child should prompt an immune evaluation. Specific granule deficiency (SGD) is a rare morphologic neutrophil granular defect characterized by reduced granules within neutrophils, absence of granule proteins, and bilobed nuclei. Patients are susce...

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Bibliographic Details
Main Authors: Maria Leszcynska, Bhumika Patel, Matthew Morrow, Wil Chamizo, Gerald Tuite, David M. Berman, Kevin Potthast, Amy P. Hsu, Steven M. Holland, Jennifer W. Leiding
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Pediatrics
Subjects:
DHR assay
specific granule deficiency
neutrophil
brain abscess in children
phagocyte
Online Access:https://www.frontiersin.org/article/10.3389/fped.2020.00117/full

Internet

https://www.frontiersin.org/article/10.3389/fped.2020.00117/full

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