Survival of Naïve T Cells Requires the Expression of Let-7 miRNAs

Survival of Naïve T Cells Requires the Expression of Let-7 miRNAs

Maintaining the diversity and constant numbers of naïve T cells throughout the organism's lifetime is necessary for efficient immune responses. Naïve T cell homeostasis, which consists of prolonged survival, occasional proliferation and enforcement of quiescence, is tightly regulated by multipl...

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Bibliographic Details
Main Authors: Elena L. Pobezinskaya, Alexandria C. Wells, Constance C. Angelou, Eric Fagerberg, Esengul Aral, Elizabeth Iverson, Motoko Y. Kimura, Leonid A. Pobezinsky
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
CD4
CD8
peripheral homeostasis
post-transcriptional
DICER
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00955/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00955/full

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