Conservation and divergence of regulatory strategies at Hox Loci and the origin of tetrapod digits.

The evolution of tetrapod limbs from fish fins enabled the conquest of land by vertebrates and thus represents a key step in evolution. Despite the use of comparative gene expression analyses, critical aspects of this transformation remain controversial, in particular the origin of digits. Hoxa and...

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Bibliographic Details
Main Authors: Joost M Woltering, Daan Noordermeer, Marion Leleu, Denis Duboule
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24465181/pdf/?tool=EBI