Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndrome

Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndrome

Breaking down the endothelial barrier is a hallmark of systemic inflammatory response syndrome. Here the authors show that palmitoylation, a post-translational modification of proteins, plays a critical role in altering endothelial function during inflammation, and suggest the targeting of palmitoyl...

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Bibliographic Details
Main Authors: Richard S. Beard, Xiaoyuan Yang, Jamie E. Meegan, Jonathan W. Overstreet, Clement G.Y. Yang, John A. Elliott, Jason J. Reynolds, Byeong J. Cha, Christopher D. Pivetti, David A. Mitchell, Mack H. Wu, Robert J. Deschenes, Sarah Y. Yuan
Format: Article
Language:English
Published: Nature Publishing Group 2016-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12823

Internet

https://doi.org/10.1038/ncomms12823

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