The Redox Role of G6PD in Cell Growth, Cell Death, and Cancer

The generation of reducing equivalent NADPH via glucose-6-phosphate dehydrogenase (G6PD) is critical for the maintenance of redox homeostasis and reductive biosynthesis in cells. NADPH also plays key roles in cellular processes mediated by redox signaling. Insufficient G6PD activity predisposes cell...

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Bibliographic Details
Main Authors: Hung-Chi Yang, Yi-Hsuan Wu, Wei-Chen Yen, Hui-Ya Liu, Tsong-Long Hwang, Arnold Stern, Daniel Tsun-Yee Chiu
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/9/1055