Gr1int/high Cells Dominate the Early Phagocyte Response to Mycobacterial Lung Infection in Mice

Lung infection by Mycobacterium tuberculosis is characterized by chronic infection of lung-resident macrophages, long considered to be the primary hosts and determinants of the outcome of the early immune response. Although alveolar macrophages are well-known to host intracellular mycobacteria at la...

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Bibliographic Details
Main Authors: Brin M. Ryder, Sarah K. Sandford, Kate M. Manners, James P. Dalton, Siouxsie Wiles, Joanna R. Kirman
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Microbiology
Subjects:
BCG
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00402/full