STING1 Promotes Ferroptosis Through MFN1/2-Dependent Mitochondrial Fusion

Ferroptosis is a type of iron-dependent regulated cell death caused by the disruption that occurs when oxidative stress and antioxidant defenses interact, and then driven by lipid peroxidation and subsequent plasma membrane ruptures. The regulation of ferroptosis involves many factors, including the...

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Bibliographic Details
Main Authors: Changfeng Li, Jiao Liu, Wen Hou, Rui Kang, Daolin Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.698679/full