Antimetastatic Effect of Halichondramide, a Trisoxazole Macrolide from the Marine Sponge Chondrosia corticata, on Human Prostate Cancer Cells via Modulation of Epithelial-to-Mesenchymal Transition

Antimetastatic Effect of Halichondramide, a Trisoxazole Macrolide from the Marine Sponge Chondrosia corticata, on Human Prostate Cancer Cells via Modulation of Epithelial-to-Mesenchymal Transition

Halichondramide (HCA), a trisoxazole-containing macrolide isolated from the marine sponge Chondrosia corticata has been shown to exhibit cytotoxicity and antifungal activities. In our previous study, HCA was also found to exhibit antiproliferative activity against a variety of cancer cells. However,...

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Bibliographic Details
Main Authors: Sang Kook Lee, Jongheon Shin, Ju-eun Jeon, Gi Dae Kim, Yoonho Shin
Format: Article
Language:English
Published: MDPI AG 2013-07-01
Series:Marine Drugs
Subjects:
halichondramide (HCA)
antimetastasis
PC3 cells
PRL-3
MMPs
Online Access:http://www.mdpi.com/1660-3397/11/7/2472

Internet

http://www.mdpi.com/1660-3397/11/7/2472

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