Internal Gene Cassette From a Human-Origin H7N9 Influenza Virus Promotes the Pathogenicity of H9N2 Avian Influenza Virus in Mice

Internal Gene Cassette From a Human-Origin H7N9 Influenza Virus Promotes the Pathogenicity of H9N2 Avian Influenza Virus in Mice

H9N2 avian influenza virus is one of the most widely circulating viruses in poultry and poses a huge potential threat to human health due to its frequent gene reassortment with other influenza viruses. In this study, we generated a series of H9N2-H7N9 reassortant viruses and examined their pathogeni...

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Bibliographic Details
Main Authors: Miaomiao Zhang, Chen Zhao, Hongjun Chen, Qiaoyang Teng, Lang Jiang, Daobin Feng, Xuesong Li, Songhua Yuan, Jianqing Xu, Xiaoyan Zhang, Zejun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Microbiology
Subjects:
avian influenza
H9N2
H7N9
internal gene
pathogenicity
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01441/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01441/full

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