Apoptotic effects of antilymphocyte globulins on human pro-inflammatory CD4+CD28- T-cells.

BACKGROUND: Pro-inflammatory, cytotoxic CD4(+)CD28(-) T-cells with known defects in apoptosis have been investigated as markers of premature immuno-senescence in various immune-mediated diseases. In this study we evaluated the influence of polyclonal antilymphocyte globulins (ATG-Fresenius, ATG-F) o...

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Bibliographic Details
Main Authors: Christina Duftner, Christian Dejaco, Paul Hengster, Klaudija Bijuklic, Michael Joannidis, Raimund Margreiter, Michael Schirmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3316508?pdf=render