Expression of Sonic Hedgehog and pathway components in the embryonic mouse head: anatomical relationships between regulators of positive and negative feedback

Expression of Sonic Hedgehog and pathway components in the embryonic mouse head: anatomical relationships between regulators of positive and negative feedback

Abstract Objective The Hedgehog pathway is a fundamental signaling pathway in organogenesis. The expression patterns of the ligand Sonic Hedgehog (Shh) and key pathway components have been studied in many tissues but direct spatial comparisons across tissues with different cell compositions and stru...

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Bibliographic Details
Main Authors: Crystal L. Sigulinsky, Xiaodong Li, Edward M. Levine
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Research Notes
Subjects:
Sonic hedgehog
Gli1
Patched
Hedgehog interacting protein
Gene expression
Retina
Online Access:https://doi.org/10.1186/s13104-021-05714-5

Internet

https://doi.org/10.1186/s13104-021-05714-5

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