Effect of different corticosteroid regimes for hospitalised patients with exacerbated COPD: pooled analysis of individual participant data from the REDUCE and CORTICO-COP trials

Effect of different corticosteroid regimes for hospitalised patients with exacerbated COPD: pooled analysis of individual participant data from the REDUCE and CORTICO-COP trials

Abstract Background Systemic corticosteroid administration for severe acute exacerbations of COPD (AECOPD) reduces the duration of hospital stays. Corticosteroid-sparing regimens have showed non-inferiority to higher accumulated dose regimens regarding re-exacerbation risk in patients with AECOPD. H...

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Bibliographic Details
Main Authors: Pradeesh Sivapalan, Jonas Rutishauser, Charlotte Suppli Ulrik, Jörg D. Leuppi, Lars Pedersen, Beat Mueller, Josefin Eklöf, Tor Biering-Sørensen, Vibeke Gottlieb, Karin Armbruster, Julie Janner, Mia Moberg, Therese S. Lapperre, Thyge L. Nielsen, Andrea Browatzki, Alexander Mathioudakis, Jørgen Vestbo, Philipp Schüetz, Jens-Ulrik Jensen
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Respiratory Research
Subjects:
COPD
Exacerbation
Corticosteroids
Mortality
Days alive and out of hospital
Intensive care unit
Online Access:https://doi.org/10.1186/s12931-021-01745-5

Internet

https://doi.org/10.1186/s12931-021-01745-5

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