NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin.

NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin.

Diabetic nephropathy (DN) is a microvascular complication of diabetes mellitus that results in both tubular and glomerular injury. Low-grade inflammation and oxidative stress are two mechanisms known to drive the progression of DN. Nucleotide-binding leucine-rich repeat containing family member X1 (...

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Bibliographic Details
Main Authors: Angelique M L Scantlebery, Melissa Uil, Loes M Butter, Renée Poelman, Nike Claessen, Stephen E Girardin, Sandrine Florquin, Joris J T H Roelofs, Jaklien C Leemans
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0214437

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https://doi.org/10.1371/journal.pone.0214437

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