Time and Antigen-Stimulation History Influence Memory CD8 T Cell Bystander Responses

Memory CD8 T cells can be activated and induced to produce cytokines and increase stores of cytolytic proteins not only in response to cognate antigen (Ag) but also in response to inflammatory cytokines (bystander responses). Importantly, bystander memory CD8 T cell functions have been shown to be d...

Full description

Bibliographic Details
Main Authors: Matthew D. Martin, Qiang Shan, Hai-Hui Xue, Vladimir P. Badovinac
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00634/full