Polycystin-2 Is Required for Starvation- and Rapamycin-Induced Atrophy in Myotubes

Polycystin-2 Is Required for Starvation- and Rapamycin-Induced Atrophy in Myotubes

Muscle atrophy involves a massive catabolism of intracellular components leading to a significant reduction in cellular and tissue volume. In this regard, autophagy, an intracellular mechanism that degrades proteins and organelles, has been implicated with muscle breakdown. Recently, it has shown th...

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Bibliographic Details
Main Authors: Catalina Kretschmar, Daniel Peña-Oyarzun, Cecilia Hernando, Nadia Hernández-Moya, Alfredo Molina-Berríos, María Paz Hernández-Cáceres, Sergio Lavandero, Mauricio Budini, Eugenia Morselli, Valentina Parra, Rodrigo Troncoso, Alfredo Criollo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Endocrinology
Subjects:
atrophy
polycystin-2
myotubes
mTOR
starvation
rapamycin
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00280/full

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https://www.frontiersin.org/article/10.3389/fendo.2019.00280/full

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