The antioxidant protein peroxiredoxin 4 is epigenetically down regulated in acute promyelocytic leukemia.

The antioxidant protein peroxiredoxin 4 is epigenetically down regulated in acute promyelocytic leukemia.

The antioxidant peroxiredoxin (PRDX) protein family comprises 6 members, which are implicated in a variety of cellular responses, including growth factor signal transduction. PRDX4 resides in the endoplasmic reticulum (ER), where it locally controls oxidative stress by reducing H(2)O(2) levels. We r...

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Bibliographic Details
Main Authors: Karishma K Palande, Renee Beekman, Lotte E van der Meeren, H Berna Beverloo, Peter J M Valk, Ivo P Touw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3024432?pdf=render

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http://europepmc.org/articles/PMC3024432?pdf=render

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