A road map from single-cell transcriptome to patient classification for the immune response to trauma

A road map from single-cell transcriptome to patient classification for the immune response to trauma

Immune dysfunction is an important factor driving mortality and adverse outcomes after trauma but remains poorly understood, especially at the cellular level. To deconvolute the trauma-induced immune response, we applied single-cell RNA sequencing to circulating and bone marrow mononuclear cells in...

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Bibliographic Details
Main Authors: Tianmeng Chen, Matthew J. Delano, Kong Chen, Jason L. Sperry, Rami A. Namas, Ashley J. Lamparello, Meihong Deng, Julia Conroy, Lyle L. Moldawer, Philip A. Efron, Patricia Loughran, Christopher Seymour, Derek C. Angus, Yoram Vodovotz, Wei Chen, Timothy R. Billiar
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-01-01
Series:JCI Insight
Subjects:
Immunology
Inflammation
Online Access:https://doi.org/10.1172/jci.insight.145108

Internet

https://doi.org/10.1172/jci.insight.145108

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