Bakuchiol Attenuates Oxidative Stress and Neuron Damage by Regulating Trx1/TXNIP and the Phosphorylation of AMPK After Subarachnoid Hemorrhage in Mice

Bakuchiol Attenuates Oxidative Stress and Neuron Damage by Regulating Trx1/TXNIP and the Phosphorylation of AMPK After Subarachnoid Hemorrhage in Mice

Subarachnoid hemorrhage (SAH) is a fatal cerebrovascular condition with complex pathophysiology that reduces brain perfusion and causes cerebral functional impairments. An increasing number of studies indicate that early brain injury (EBI), which occurs within the first 72 h of SAH, plays a crucial...

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Bibliographic Details
Main Authors: Haixiao Liu, Wei Guo, Hao Guo, Lei Zhao, Liang Yue, Xia Li, Dayun Feng, Jianing Luo, Xun Wu, Wenxing Cui, Yan Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
bakuchiol
subarachnoid hemorrhage
early brain injury
oxidative stress
apoptosis
thioredoxin
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00712/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.00712/full

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