Da-Bu-Yin-Wan Improves the Ameliorative Effect of DJ-1 on Mitochondrial Dysfunction Through Augmenting the Akt Phosphorylation in a Cellular Model of Parkinson’s Disease

Da-Bu-Yin-Wan (DBYW) is recorded originally in China over six centuries ago, and it is used to treat Parkinson’s disease (PD) clinically in recent decades. DJ-1 is a homodimeric protein linked to early-onset PD, and found in the mitochondria. In addition, DJ-1 could protect the cells by regulating g...

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Bibliographic Details
Main Authors: Yi Zhang, Xiao-Gang Gong, Hong-Mei Sun, Zhen-Yu Guo, Jing-Hong Hu, Yuan-Yuan Wang, Wan-Di Feng, Lin Li, Ping Li, Zhen-Zhen Wang, Nai-Hong Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Pharmacology
Subjects:
Akt
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01206/full