Parathyroid Hormone-Related Protein Negatively Regulates Tumor Cell Dormancy Genes in a PTHR1/Cyclic AMP-Independent Manner
Parathyroid hormone-related protein (PTHrP) expression in breast cancer is enriched in bone metastases compared to primary tumors. Human MCF7 breast cancer cells “home” to the bones of immune deficient mice following intracardiac inoculation, but do not grow well and stain negatively for Ki67, thus...
Main Authors: | Rachelle W. Johnson, Yao Sun, Patricia W. M. Ho, Audrey S. M. Chan, Jasmine A. Johnson, Nathan J. Pavlos, Natalie A. Sims, T. John Martin |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-05-01
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Series: | Frontiers in Endocrinology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fendo.2018.00241/full |
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