Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations

Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations

The current model for reverse cholesterol transport proposes that HDL transports excess cholesterol derived primarily from peripheral cells to the liver for removal. However, recent studies in ABCA1 transgenic mice suggest that the liver itself may be a major source of HDL cholesterol (HDL-C). To di...

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Bibliographic Details
Main Authors: Federica Basso, Lita Freeman, Catherine L. Knapper, Alan Remaley, John Stonik, Edward B. Neufeld, Terese Tansey, Marcelo J.A. Amar, Jamila Fruchart-Najib, Nicholas Duverger, Silvia Santamarina-Fojo, H.Bryan Brewer, Jr.
Format: Article
Language:English
Published: Elsevier 2003-02-01
Series:Journal of Lipid Research
Subjects:
reverse cholesterol transport
lipoprotein
cholesterol
Tangier disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520312165

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http://www.sciencedirect.com/science/article/pii/S0022227520312165

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