Interaction of Lactoferrin with Unsaturated Fatty Acids: In Vitro and In Vivo Study of Human Lactoferrin/Oleic Acid Complex Cytotoxicity

Interaction of Lactoferrin with Unsaturated Fatty Acids: In Vitro and In Vivo Study of Human Lactoferrin/Oleic Acid Complex Cytotoxicity

As shown recently, oleic acid (OA) in complex with lactoferrin (LF) causes the death of cancer cells, but no mechanism(s) of that toxicity have been disclosed. In this study, constitutive parameters of the antitumor effect of LF/OA complex were explored. Complex LF/OA was prepared by titrating recom...

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Bibliographic Details
Main Authors: Anna Elizarova, Alexey Sokolov, Valeria Kostevich, Ekaterina Kisseleva, Evgeny Zelenskiy, Elena Zakharova, Oleg Panasenko, Alexander Budevich, Igor Semak, Vladimir Egorov, Giulia Pontarollo, Vincenzo De Filippis, Vadim Vasilyev
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Materials
Subjects:
lactoferrin
oleic acid
tumor growth
anticancer drugs
Online Access:https://www.mdpi.com/1996-1944/14/7/1602

Internet

https://www.mdpi.com/1996-1944/14/7/1602

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