Feedback regulation of cytoneme-mediated transport shapes a tissue-specific FGF morphogen gradient

Feedback regulation of cytoneme-mediated transport shapes a tissue-specific FGF morphogen gradient

Gradients of signaling proteins are essential for inducing tissue morphogenesis. However, mechanisms of gradient formation remain controversial. Here we characterized the distribution of fluorescently-tagged signaling proteins, FGF and FGFR, expressed at physiological levels from the genomic knock-i...

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Bibliographic Details
Main Authors: Lijuan Du, Alex Sohr, Ge Yan, Sougata Roy
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-10-01
Series:eLife
Subjects:
FGF
morphogen gradient
cytonemes
Drosophila
FGFR
branching morphogenesis
Online Access:https://elifesciences.org/articles/38137

Internet

https://elifesciences.org/articles/38137

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