Playing Jekyll and Hyde—The Dual Role of Lipids in Fatty Liver Disease

Lipids play Jekyll and Hyde in the liver. On the one hand, the lipid-laden status of hepatic stellate cells is a hallmark of healthy liver. On the other hand, the opposite is true for lipid-laden hepatocytes—they obstruct liver function. Neglected lipid accumulation in hepatocytes can progress into...

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Bibliographic Details
Main Authors: Martijn R. Molenaar, Louis C. Penning, J. Bernd Helms
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/10/2244