Patient-Derived Induced Pluripotent Stem Cell-Based Models in Parkinson’s Disease for Drug Identification

Patient-Derived Induced Pluripotent Stem Cell-Based Models in Parkinson’s Disease for Drug Identification

Parkinson’s disease (PD) is a common progressive neurodegenerative disorder characterized by loss of striatal-projecting dopaminergic neurons of the ventral forebrain, resulting in motor and cognitive deficits. Despite extensive efforts in understanding PD pathogenesis, no disease-modifying drugs ex...

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Bibliographic Details
Main Authors: Georgia Kouroupi, Nasia Antoniou, Kanella Prodromidou, Era Taoufik, Rebecca Matsas
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
disease phenotypes
high-content screening
chemical libraries
disease-modifying drugs
hiPSC-derived neurons
hiPSC-based co-culture systems
Online Access:https://www.mdpi.com/1422-0067/21/19/7113

Internet

https://www.mdpi.com/1422-0067/21/19/7113

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