Podocyte-derived microparticles promote proximal tubule fibrotic signaling via p38 MAPK and CD36
Tubulointerstitial fibrosis is a hallmark of advanced diabetic kidney disease that is linked to a decline in renal function, however the pathogenic mechanisms are poorly understood. Microparticles (MPs) are 100–1000 nm vesicles shed from injured cells that are implicated in intercellular signalling....
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2018-12-01
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Series: | Journal of Extracellular Vesicles |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/20013078.2018.1432206 |