Observations on the use of Bruton’s tyrosine kinase inhibitors in SAR-CoV-2 and cancer

Abstract Bruton’s tyrosine kinase (BTK) inhibitors, drugs utilized in cancer, are being repurposed for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) (COVID-19). Recently, BTK inhibitors acalabrutinib and ibrutinib have been found to protect against pulmonary injury in a small group of...

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Bibliographic Details
Main Authors: Brooke Benner, William E. Carson
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13045-020-00999-8