Inosine enhances axon sprouting and motor recovery after spinal cord injury.

Although corticospinal tract axons cannot regenerate long distances after spinal cord injury, they are able to sprout collateral branches rostral to an injury site that can help form compensatory circuits in cases of incomplete lesions. We show here that inosine enhances the formation of compensator...

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Bibliographic Details
Main Authors: Daniel Kim, Laila Zai, Peng Liang, Colleen Schaffling, David Ahlborn, Larry I Benowitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3846725?pdf=render