The impact of RASopathy-associated mutations on CNS development in mice and humans

Abstract The RAS signaling pathway is involved in the regulation of developmental processes, including cell growth, proliferation, and differentiation, in the central nervous system (CNS). Germline mutations in the RAS signaling pathway genes are associated with a group of neurodevelopmental disorde...

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Bibliographic Details
Main Authors: Minkyung Kang, Yong-Seok Lee
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Molecular Brain
Subjects:
RAS
Online Access:http://link.springer.com/article/10.1186/s13041-019-0517-5