The impact of RASopathy-associated mutations on CNS development in mice and humans
Abstract The RAS signaling pathway is involved in the regulation of developmental processes, including cell growth, proliferation, and differentiation, in the central nervous system (CNS). Germline mutations in the RAS signaling pathway genes are associated with a group of neurodevelopmental disorde...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2019-11-01
|
Series: | Molecular Brain |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13041-019-0517-5 |