Superoxide dismutase overexpression protects dopaminergic neurons in a Drosophila model of Parkinson's disease
Parkinson's disease (PD) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Some of the inherited forms of the disease are caused by mutations in the α-synuclein gene and the triplication of its locus. Oxidative stress has been proposed as a...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2008-04-01
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| Series: | Neurobiology of Disease |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996107002719 |