Identification of pain categories associated with change in pain in patients receiving placebo: data from two phase 3 randomized clinical trials in symptomatic knee osteoarthritis

Identification of pain categories associated with change in pain in patients receiving placebo: data from two phase 3 randomized clinical trials in symptomatic knee osteoarthritis

Abstract Background Pain is the principal clinical symptom of osteoarthritis (OA), and development of safe and effective analgesics for OA pain is needed. Drug development of new analgesics for OA pain is impaired by substantial change in pain in patients receiving placebo, and more data describing...

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Bibliographic Details
Main Authors: Asger Reinstrup Bihlet, Inger Byrjalsen, Anne-Christine Bay-Jensen, Jeppe Ragnar Andersen, Claus Christiansen, Bente Juel Riis, Ivo Valter, Morten A. Karsdal, Marc C. Hochberg
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Musculoskeletal Disorders
Subjects:
Pain categories
Placebo-response
Radiographic progression
Online Access:http://link.springer.com/article/10.1186/s12891-018-1938-5

Internet

http://link.springer.com/article/10.1186/s12891-018-1938-5

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