No significant difference between ceftriaxone and cefotaxime in the emergence of antibiotic resistance in the gut microbiota of hospitalized patients: A pilot study

No significant difference between ceftriaxone and cefotaxime in the emergence of antibiotic resistance in the gut microbiota of hospitalized patients: A pilot study

Background: Ceftriaxone and cefotaxime share a similar antibacterial spectrum and similar indications but have different pharmacokinetic characteristics. Ceftriaxone is administered once daily and 40% of its clearance is by biliary elimination, whereas cefotaxime requires three administrations per d...

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Bibliographic Details
Main Authors: Benoît Pilmis, Olivier Jiang, Assaf Mizrahi, Jean-Claude Nguyen Van, Julie Lourtet-Hascoët, Olivier Voisin, Erwan Le Lorc’h, Sidonie Hubert, Elodie Ménage, Philippe Azria, Marie-Françoise Borie, Annabelle Mahé, Jean-Jacques Mourad, Eloïse Trabattoni, Olivier Ganansia, Jean-Ralph Zahar, Alban Le Monnier
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:International Journal of Infectious Diseases
Subjects:
Gut microbiota
Third generation cephalosporin
Extended spectrum beta-lactamase
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971221000357

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http://www.sciencedirect.com/science/article/pii/S1201971221000357

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