Investigating the Glucagon Receptor and Glucagon-Like Peptide 1 Receptor Activity of Oxyntomodulin-Like Analogues in Male Wistar Rats

Investigating the Glucagon Receptor and Glucagon-Like Peptide 1 Receptor Activity of Oxyntomodulin-Like Analogues in Male Wistar Rats

Aims: To investigate the effect of Glu-3 OXM-like analogues on food intake and bodyweight in male rats. Background: Oxyntomodulin (OXM) is a natural agonist at both the glucagon receptor (GCGr) and the glucagon-like peptide 1 receptor (GLP-1r), and peripheral administration reduces food intake and i...

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Bibliographic Details
Main Authors: Samantha L. Price, MRes, James S. Minnion, PhD, Stephen R. Bloom, MD
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Current Therapeutic Research
Subjects:
analogue
body weight
glucagons
oxyntomodulin
Online Access:http://www.sciencedirect.com/science/article/pii/S0011393X15000156

Internet

http://www.sciencedirect.com/science/article/pii/S0011393X15000156

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