Investigating the Glucagon Receptor and Glucagon-Like Peptide 1 Receptor Activity of Oxyntomodulin-Like Analogues in Male Wistar Rats
Aims: To investigate the effect of Glu-3 OXM-like analogues on food intake and bodyweight in male rats. Background: Oxyntomodulin (OXM) is a natural agonist at both the glucagon receptor (GCGr) and the glucagon-like peptide 1 receptor (GLP-1r), and peripheral administration reduces food intake and i...
Main Authors: | Samantha L. Price, MRes, James S. Minnion, PhD, Stephen R. Bloom, MD |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-12-01
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Series: | Current Therapeutic Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0011393X15000156 |
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