Cytotoxic 4-Hydroxyprorocentrolide and Prorocentrolide C from Cultured Dinoflagellate<i> Prorocentrum lima </i>Induce Human Cancer Cell Death through Apoptosis and Cell Cycle Arrest
Prorocentrolide and its analogs, the novel naturally derived antitumor agents, have recently been identified in the dinoflagellate <i>Prorocentrum lima</i>. In the current study, the underlying inhibitory mechanisms of 4-hydroxyprorocentrolide (<b>1</b>) and prorocentrolide C...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-05-01
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Series: | Toxins |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6651/12/5/304 |