Global Trends in Proteome Remodeling of the Outer Membrane Modulate Antimicrobial Permeability in Klebsiella pneumoniae

Global Trends in Proteome Remodeling of the Outer Membrane Modulate Antimicrobial Permeability in Klebsiella pneumoniae

Klebsiella pneumoniae is a pathogen of humans with high rates of mortality and a recognized global rise in incidence of carbapenem-resistant K. pneumoniae (CRKP). The outer membrane of K. pneumoniae forms a permeability barrier that modulates the ability of antibiotics to reach their intracellular t...

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Bibliographic Details
Main Authors: Andrea Rocker, Jake A. Lacey, Matthew J. Belousoff, Jonathan J. Wilksch, Richard A. Strugnell, Mark R. Davies, Trevor Lithgow
Format: Article
Language:English
Published: American Society for Microbiology 2020-04-01
Series:mBio
Subjects:
antimicrobial resistance
porin
ompk37
beta-barrel
carbapenem
carbapenems
porins
Online Access:https://doi.org/10.1128/mBio.00603-20

Internet

https://doi.org/10.1128/mBio.00603-20

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