Resistance to first-line anti-TB drugs is associated with reduced nitric oxide susceptibility in Mycobacterium tuberculosis.

Resistance to first-line anti-TB drugs is associated with reduced nitric oxide susceptibility in Mycobacterium tuberculosis.

The relative contribution of nitric oxide (NO) to the killing of Mycobacterium tuberculosis in human tuberculosis (TB) is controversial, although this has been firmly established in rodents. Studies have demonstrated that clinical strains of M. tuberculosis differ in susceptibility to NO, but how th...

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Bibliographic Details
Main Authors: Jonna Idh, Mekidim Mekonnen, Ebba Abate, Wassihun Wedajo, Jim Werngren, Kristian Ängeby, Maria Lerm, Daniel Elias, Tommy Sundqvist, Abraham Aseffa, Olle Stendahl, Thomas Schön
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3387217?pdf=render

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http://europepmc.org/articles/PMC3387217?pdf=render

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