Anti-Nociceptive, Analgesic and Pathohistological Effects of Intrathecal Dexmedetomidine and Bupivacaine in Rats

Background and Objectives: This study investigates analgesic and nociceptive effects of adding dexmedetomidine to bupivacaine neuraxial anesthesia through Tail-flick (TF) and Hot-plate (HP) tests and the pathohistological changes on spinal nerves and nerve roots through light microscopy. Methods: For...

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Bibliographic Details
Main Authors: Başar Erdivanli, Murat Altun, Özlem K. Sezen, Serhan A. Çolakoğlu
Format: Article
Language:English
Published: Elsevier 2013-03-01
Series:Brazilian Journal of Anesthesiology
Online Access:http://www.sciencedirect.com/science/article/pii/S0104001413000353