A microfluidic device for preparing next generation DNA sequencing libraries and for automating other laboratory protocols that require one or more column chromatography steps.

A microfluidic device for preparing next generation DNA sequencing libraries and for automating other laboratory protocols that require one or more column chromatography steps.

Library preparation for next-generation DNA sequencing (NGS) remains a key bottleneck in the sequencing process which can be relieved through improved automation and miniaturization. We describe a microfluidic device for automating laboratory protocols that require one or more column chromatography...

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Bibliographic Details
Main Authors: Swee Jin Tan, Huan Phan, Benjamin Michael Gerry, Alexandre Kuhn, Lewis Zuocheng Hong, Yao Min Ong, Polly Suk Yean Poon, Marc Alexander Unger, Robert C Jones, Stephen R Quake, William F Burkholder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3722208?pdf=render

Internet

http://europepmc.org/articles/PMC3722208?pdf=render

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